First off, let's remember that adapalene can be purchased without a prescription, which is a big positive.
Adapalene and tretinoin are both topical retinoids that can treat acne. The main difference between them is that tretinoin has also been proven to improve the visible signs of skin aging, such as wrinkles, dark spots, and hyperpigmentation.
Tretinoin may show faster improvement than adapalene, but it may also cause more skin irritation. Adapalene is generally better tolerated by all skin types.
