Issue #7 | July 2025

Announcements

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Please have a fun and safe holiday weekend.



Welcome New Hires!


Many sites are onboarding new staff and we are excited to have them joining the team. Thank you to all the coordinators who have made THRIVE a success to this point and are now moving on to new adventures.


If you are adding or removing team members, please remember to complete this Qualtrics form so we can quickly start trainings or remove access as appropriate.


Operational Update

Target Randomization: 13,000

Randomization counts as of July 3, 2025

Institution

Total Randomized

Institution

Total Randomized

Brigham and Women’s Hospital

153

University of California San Francisco

1,289

Dartmouth-Hitchcock Medical Center

94

University of Michigan

620

Duke University Hospital

306

University of Pennsylvania

48

Henry Ford Detroit

162

University of Utah

484

Massachusetts General Hospital

116

University of Virginia Health System

161

MD Anderson

544

University of Washington

141

NYU Langone Medical Center

81

Wake Forest School of Medicine

137

Oregon Health Science University

91

Washington University

729

Stanford University

7

Weill Cornell Medical College

440

University of Arkansas

107

Yale New Haven Hospital

552



TOTAL:

6,262

96.0%


POD1 QoR15

99.4%


POD1 or POD30 Brice

98.1%


TIVA Adherence

99.8%


INVA Adherence

Updated Resources with INVA/Propofol Guidance

The following documents have been updated with language to reflect the new guidance to not use Propofol infusions in INVA cases.


TIVA INVA Reminder Cards

Anesthesia Clinician FAQ

THRIVE CRC FAQ

Email to Anesthesia Team BEFORE surgery

THRIVE Overview for Anesthesia Clinicians


Fire Drill! Where (and What) is Your Downtime Packet?

Do you know where your downtime packet is? What about the newest members of your team?


Every site was mailed a packet of paper documents and envelopes for use in the event that randomization or other time-sensitive activities could not be completed in MQUARK or MyDataHelps.


Each packet includes:

  • 10 sealed envelopes for manual randomization
  • MQUARK DOS form
  • SAE forms
  • UB-CAM survey
  • 3D-CAM survey
  • EQ-5D-5L survey
  • WHODAS 2.0 survey
  • QoR-15 survey
  • Modified Brice survey


Emerging Literature

How Patient Partners Helped Refine an Intraoperative Awareness Screening Tool


The modified Brice questionnaire is an effective screening tool for intraoperative awareness with recall, but the core questions of this survey have never before been reviewed by patients for accessibility and understanding.


The modified Brice questionnaire provides a key outcome for THRIVE and our Patient Partner Panel provided specific feedback on how to make the language of the questionnaire more accessible to patients. Their recommendations were put into practice for the Full Scale phase of the study.


Click here to read more about how our Patient Partners drove change on this important questionnaire.

Getting to Know the Team - University of Virginia

Bhiken Naik, MBBCh, MSCR

University of Virginia


Bhiken Naik, MBBCh, MSCR, is Vice Chair for Clinical Research and Professor of Anesthesiology and Neurological Surgery at the University of Virginia, where he also serves as Associate Director of the Neuroscience Intensive Care Unit. His research spans major spine surgery, perioperative hemostasis, acute kidney injury, and opioid management. His recent work focuses on advancing data equity in low- and middle-income countries through real-time digitization of perioperative anesthesia records using computer vision and artificial intelligence. Dr. Naik views THRIVE as a critical opportunity to better understand foundational aspects of anesthesia care with both immediate and long-term implications for patient outcomes.



Lucas Fernandez, MD DSc

University of Virginia



Dr. Lucas Fernandez received both his MD and DSc degrees from the University of Zulia in Maracaibo, Venezuela. He spent 15 years working in basic science—focusing on molecular biology and animal physiology—at the University of Virginia before transitioning into clinical research. Currently, as one of the CRCs involved in the THRIVE study, Dr. Fernandez is passionate about improving patient care and contributing to advancements in anesthesia practice. A fun fact about Dr. Fernandez: he is proud to have met and co-authored a paper with the 2007 Nobel Prize winner in Physiology or Medicine, Dr. Oliver Smithies.


Avani Jain, MBBS

University of Virginia


Dr. Avani Jain is currently working as a Clinical Research Coordinator on the THRIVE study. She holds an MBBS degree and a Master’s in Medical Informatics from the University of Missouri. Her professional interests lie in patient-centered research, and she truly enjoys collaborating with physicians, CRNAs, residents, and research teams to explore and discuss clinical cases. Being part of the THRIVE study has given her the opportunity to connect with a diverse group of professionals and deepen her understanding of tools like the 3D CAM. She is particularly excited to see the study outcomes, as believes they have the potential to significantly influence patient care practices. Outside of work, she enjoys horse riding and creating Madhubani paintings, both of which keep her balanced and inspired.

Emily Degen

University of Virginia


Emily Degen is a Clinical Research Coordinator with UVA’s Department of Anesthesiology.  She has over 9 years of experience in the medical field as a CMA but is new to research. Before this position she worked in a busy rural family medicine clinic. She is passionate about advancing medical science and improving patient outcomes. Participating in Thrive has allowed her to experience how large, multi- site studies are organized as well as reinforced how integral good communication and cooperation is within a team.  Outside of work she enjoys reading, gardening, and snuggling her cat.  

Suggestion Box

Suggestion Box


We would love to hear from you! Please let us know if there is a team member you would like to recognize or celebrate in the next newsletter, or if there are other updates you would like to know about.


Funded by

Contract 2020C3-21106