September 2021
Looking ahead to ISHI 32...
Sept. 14-16 | Orlando, FL Booth #1212 | Attend Virtually!
Speaker
A Proteos Program Retrospective: Establishing Protein Sequencing for Forensic Analysis

Curt Hewitt, Ph.D.

Thursday September 16th, 2021 
9:30 am - 9:55 am | Fiesta Ballroom


Poster Presentation
Developmental Validation of the Illumina Infinium® Assay using the Global Screening Array on the iScan® System for use in Forensic Laboratories

David Russell, M.S.
Collaboration with UNTHSC Yields Open Source Tool for SNP-Based Kinship Analysis, Testing, and Evaluation
Center for Advanced Genomics scientists developed an open-source R package that provides consistent and intuitive data software solutions for common analyses in SNP-based kinship analysis and benchmarking. The skater package provides a suite of well-documented tools for importing, parsing, and analyzing pedigree data, performing relationship degree inference, benchmarking relationship degree classification, and summarizing IBD segment data.
The software is open-source and freely available.
For more information, read the open-access pre-print here.
The CAG is Expanding its FGG Offering
“We want to enable investigation of samples that so far have not been considered eligible for FGG.” – Christina Neal, CAG research team lead
The Center for Advanced Genomics® is validating the Verogen ForenSeq® Kintelligence workflow for the NDIS-approved MiSeq FGx® Sequencing System.


Highlights from the CAG research team’s testing:
 
  • Sensitivity results using an optimized method are down to 0.05 ng DNA input.
  • In nonprobative testing, six bone samples (i.e., burned, cremated, surface decomposition, and embalmed), starting as low as 0.04 ng/µL, were evaluated at 1 ng DNA input.
  • These samples resulted in 9934 ± 258 called SNP sites, equivalent to a 97.1 ± 2.5% call rate, when sequenced in a 4-sample multiplex.
  • Key features of the ForenSeq Kintelligence workflow:
  • Accommodates up to 25 µL sample volume - a big advantage for challenging samples.
  • The mean amplicon size is <150 bp, which is compatible with degraded samples.

Coming Soon: The CAG is on track to offer the validated ForenSeq Kintelligence workflow to its FGG clients beginning this Fall!
Grow Your Forensic DNA Career with Us!
Signature Science is hiring experienced Forensic DNA Analysts at our headquarters in Austin, Texas. As an analyst, you’ll collaborate with experts in the field of Forensic Science - and beyond - as an integral part of The Center for Advanced Genomics.

At our ANAB-accredited laboratory, SigSci analysts work to support a robust, growing client base, and can expect to be challenged daily with a diversified caseload. Our analysts are trained in all aspects of forensic casework, and, as a result, can enjoy start-to-finish case ownership. Learn more about Forensic DNA testing at SigSci here and apply to start a rewarding career at Signature Science today!


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