Discover cutting-edge diagnostics with David R. Walt:
Center to host microwell array pioneer for special lecture and open house breakfast — September 12 | 9 a.m. – 12:30 p.m.
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The Center for RNA Biomedicine is thrilled to host David R. Walt, Ph.D., for a lecture entitled,
"Why sensitivity matters for clinical diagnosis."
Following the lecture, join us for a complimentary breakfast and open house hosted by the Center for RNA Biomedicine in the Henderson Room (directly across the hall), where you can engage with Dr. Walt and fellow attendees.
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About the Speaker:
Dr. David R. Walt is the Hansjörg Wyss Professor at Harvard Medical School and a Professor of Pathology at Brigham and Women’s Hospital. He developed breakthrough optical microwell arrays and single-molecule detection technologies. As the founder of Illumina Inc. and Quanterix Corp., and co-founder of other startups, Dr. Walt has significantly advanced life sciences. His honors include the 2023 Russ Prize and the 2021 Kabiller Prize. He is a member of the U.S. National Academy of Engineering and Medicine.
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Location:
3rd Floor | Michigan League
Schedule:
9 a.m. | Lecture | Koessler Room
10 a.m. | Open House | Henderson Room
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Due to popular demand, a hybrid option will be available via Zoom.
If you can't attend in person, please join us virtually.
Click here to register for the Zoom.
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Don't miss this unique opportunity to learn from a leading expert in the field. We look forward to seeing you there! | |
Michigan Medicine's Rogel Cancer Center honors multiple Center for RNA Biomedicine members with new roles and grants | |
Prensner chosen for Rogel Cancer Center council advocating for early career faculty | |
John Prensner, M.D., Ph.D., has been selected to serve on the Rogel Cancer Center's Emerging Leaders Council (ELC).
You can learn more about the Rogel Cancer Center's ELC work to empower and advocate for early career faculty in this 2022 article by Eric Olsen on Rogel's website.
| Congratulations, John, and all others selected to serve! | |
Multiple center members named 2024 Rogel Scholars | |
Five Center for RNA Biomedicine faculty members have been added to the 2024 Class of Rogel Scholars.
Honored center faulty in the 2024 Class of Rogel Scholars are:
You can learn more about the Rogel Scholars, and the honored center faculty chosen in a new article by Paul Avedisian on the Center for RNA Biomedicine website.
Congratulations Ben, Grace, Justin, Analisa, and Deepak!
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Chinnaiyan studies indirect inhibition of oncogenic transcription factors for cancer treatment | | |
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Center faculty member, Arul Chinnaiyan, M.D., Ph.D., was recently featured in a Michigan Medicine Health Lab article, "Research finds possible therapies to target oncogenic transcription factors in multiple cancer types" by Anna Megdell. The article details research in which Chinnaiyan and his team are engaged — delving into "the potential of developing new cancer treatments to target oncogenic transcription factors by indirectly affecting their ability to access enhancer DNA in chromatin."
Read more about important work being done by center members in this Health Lab article.
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The Chemistry Seminar Series:
"Protein dynamics: Connecting in vitro, in cell, and in vivo"
Caitlin Davis, Ph.D. | Yale Medical School
TODAY — Tuesday, September 3 | 4 p.m.
Chemistry Building| Rm. 1640
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Biomedical Engineering Seminar Series:
"Development of genome editing approaches to treat cystic fibrosis and other disorders"
Sriram Vaidyanathan, Ph.D. | Nationwide Children’s Hospital
Thursday, September 5 | 3:30 p.m.
Lurie Biomed. Engineering | Rm. 1130
Join via Zoom by clicking here.
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Life Sciences Institute — Seminar of Interest:
"Squaring the circle? — Mechanistic studies of translation initiation on natural, coding circular RNAs in eukaryotes"
Philipp Zuber, Ph.D. | MRC Laboratory of Molecular Biology
Tuesday, September 5 | 3:30 p.m.
LSI Library
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Advanced Genomics Core Symposium
Learn how single-cell and spatial technologies can be tailored for your research. Hear from experts, learn about advanced developments, and get one-on-one interaction with the Advanced Genomics Core team and 10x.
Thursday, September 5 | 9 a.m. – 5 p.m.
Click here for registration and more information.
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"Development of native ion mobility-mass spectrometry methods for the analysis of membrane proteins from various membrane mimetics"
Iliana Levesque | Chemistry
Wednesday, September 4 | 2 p.m.
East Conference Room — 4th Fl. — Rackham
Advisor: Brandon Thomas Ruotolo, Ph.D.
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"Metabolic targets for ehanced therapy of pancreatic cancer"
Noah Meurs | Biomedical Engineering
Friday, September 6 | 3 p.m.
NCRC — Bldg. 300 — Rm. 376
Advisor: Deepak Nagrath, Ph.D.
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"Chemical engineering multiomics integrative analysis for delineating genetic variants in metabolic (dysfunction) associated fatty liver diseases (MAFLD)"
Olamide Animasahun | Chemical Engineering
Friday, September 13 | 2 p.m.
NCRC — Bldg. 10 — Rm. G065
Advisor: Deepak Nagrath, Ph.D.
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Our members' publications are available through Altmetric.
Queries currently available:
CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.
Below are recent highlights.
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Mittal P, Myers JA, Carter RD, Radko-Juettner S, Malone HA, Rosikiewicz W, Robertson AN, Zhu Z, Narayanan IV, Hansen BS, Parrish M, Bhanu NV, Mobley RJ, Rehg JE, Xu B, Drosos Y, Pruett-Miller SM, Ljungman M, Garcia BA, Wu G, Partridge JF, Roberts CWM. PHF6 cooperates with SWI/SNF complexes to facilitate transcriptional progression. Nat Commun. 2024 Aug 24;15(1):7303. doi: 10.1038/s41467-024-51566-5. PMID: 39181868; PMCID: PMC11344777. | | |
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Wan M, Liu Y, Li D, Snyder RJ, Elkin LB, Day CR, Rodriguez J, Grunseich C, Mahley RW, Watts JA, Cheung VG. The enhancer RNA, AANCR, regulates APOE expression in astrocytes and microglia. Nucleic Acids Res. 2024 Aug 20:gkae696. doi: 10.1093/nar/gkae696. Epub ahead of print. PMID: 39162226. | | |
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Kim J, Xu S, Jung SR, Nguyen A, Cheng Y, Zhao M, Fujimoto BS, Nelson W, Schiro P, Franklin JL, Higginbotham JN, Coffey RJ, Shi M, Vojtech LN, Hladik F, Tewari M, Tigges J, Ghiran I, Jovanovic-Talisman T, Laurent LC, Das S, Gololobova O, Witwer KW, Xu T, Charest A, Jensen KVK, Raffai RL, Jones JC, Welsh JA, Nolan JP, Chiu DT. Comparison of EV characterization by commercial high-sensitivity flow cytometers and a custom single-molecule flow cytometer. J Extracell Vesicles. 2024 Aug;13(8):e12498. doi: 10.1002/jev2.12498. PMID: 39140467; PMCID: PMC11322860. | | |
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Brito Querido J, Sokabe M, Díaz-López I, Gordiyenko Y, Zuber P, Du Y, Albacete-Albacete L, Ramakrishnan V, Fraser CS. Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit. Nat Commun. 2024 Aug 8;15(1):6633. doi: 10.1038/s41467-024-50672-8. PMID: 39117603; PMCID: PMC11310195. | | |
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Yee C, Xiao Y, Chen H, Reddy AR, Xu B, Medwig-Kinney TN, Zhang W, Boyle AP, Herbst WA, Xiang YK, Matus DQ, Shen K. An activity-regulated transcriptional program directly drives synaptogenesis. Nat Neurosci. 2024 Aug 5. doi: 10.1038/s41593-024-01728-x. Epub ahead of print. PMID: 39103556. | | |
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Conn VM, Chinnaiyan AM, Conn SJ. Circular RNA in cancer. Nat Rev Cancer. 2024 Sep;24(9):597-613. doi: 10.1038/s41568-024-00721-7. Epub 2024 Jul 29. PMID: 39075222. | | |
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The Istituto Italiano di Tecnologia's (IIT's) RNA Technologies flagship is seeking to appoint a Scientific Project Manager that will have a key research role on planning, managing, monitoring and implementing all the activities necessary for the successful completion of internal and external projects for which IIT is the Coordinator.
Click here for more details and to apply.
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Six fully-funded, four-year Ph.D. projects in Italy.
Projects are shared across different labs in the Isituto Italiano di Tecnologia — RNA flagship and address various topics on our favorite molecule. RNA.
Click here to learn more.
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For complete details on current openings and how to apply for these positions, visit the Recruitment Opportunities page on our website. | | | | |
