Are you living with brain or leptomeningeal metastasis from breast cancer? You are not alone.

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CLINICAL TRIALS

NEW Featured Clinical Trials

*MBCBrainMets.org is currently featuring clinical trials led by our

Medical Advisory Board. Not every clinical trial is a good match for every patient, but there are many ongoing and new clinical trials for patients living with MBC brain mets and leptomeningeal disease. We hope you find it a helpful way to learn about one of the trials currently recruiting patients.

ReSPECT-LM Clinical Trial

Watch the video below to hear Priya Kumthekar, Neuro-Oncologist at Northwestern Medicine, discuss the ReSPECT-LM Clinical Trial.

The ReSPECT-LM clinical trial by Plus Therapeutics tests a new radiotherapeutic, Rhenium (186Re) Obisbemeda, for Leptomeningeal Metastases. Patients receive a single dose via a small catheter under the scalp in under 5 minutes, with same day discharge from the hospital.

Watch Video Here

Find a Trial that's Right for you

Below you will find the first and only clinical trial search tool designed specifically for patients with brain metastasis or leptomeningeal disease from breast cancer. To view examples of ongoing clinical trials for Stage IV MBC brain metastasis or leptomeningeal disease, visit our Find a Clinical Trial page.

RESOURCES

NEW Research Articles

We are thrilled to announce that we have new research articles available for you to explore. Stay informed and up-to-date with the latest findings.

Real-world outcomes in patients with brain metastases secondary to HR+/HER2− MBC treated with abemaciclib and local intracranial therapy

Real-world data on brain metastases in metastatic breast cancer (MBC) patients treated with CDK4/6 inhibitors are limited. A recent study examines outcomes in HR+/HER2− MBC patients with brain metastases diagnosed before starting abemaciclib, providing valuable insights into this population.

Brain Metastasis in Triple-Negative Breast Cancer

Breast cancer is a leading cause of cancer-related deaths in women and the second most common source of brain metastases. This study reviewed TNBC cases (2000–2014) at the Instituto Nacional de Enfermedades Neoplásicas to understand characteristics and outcomes of those who developed brain metastases.

A Phase II Study of Atezolizumab, Pertuzumab, and High-Dose Trastuzumab for Central Nervous System Metastases in Patients with HER2-Positive Breast Cancer

Patients with HER2-positive breast cancer brain metastases have limited systemic therapy options. This single-arm, multi center study explores whether adding atezolizumab to high-dose trastuzumab and pertuzumab, previously shown to have CNS benefits, could improve outcomes.

PATIENT CORNER

Would you like to Share your Story?

We want to hear from YOU!

We have two different opportunities for you to share your story: blog and video. Your patient voice and story matters. Sharing your story can provide hope and inspiration to others diagnosed or undergoing treatment.

Patient Blog

Would you like to write about your story? For questions or to submit your blog, please email mbcbrainmets@gmail.com for guidance.

No patient should have to go through MBC brain metastasis alone. Read some of our patient stories which are vulnerable, honest, and poignant.

Read Patient Stories Here

Patient Video

If you are interested in creating a video, please email mbcbrainmets@gmail.com for guidance.

Take a look at the videos from patients living with brain metastasis who share their experiences of receiving a brain metastasis diagnosis, participating in a clinical trial, and undergoing treatments like a craniotomy, whole brain radiation, and others.

Watch Patient Stories Here

SUPPORT SERVICES

Support Group

Breast Cancer Brain Mets (BCBM) Support Group

This is a Zoom Support Group meeting twice a month from 3:00-4:30 ET. The group is for women of all ages who have been diagnosed with brain metastases or leptomeningeal disease from breast cancer. Please join us to find hope, support and information from others living with this disease.

Registration is required for new participants.

Are you living with brain or leptomeningeal metastasis from breast cancer? You are not alone.﻿