Thank you to all 2023 PSC Partners Annual Conference attendees, presenters, and sponsors. The weekend was packed with educational sessions, supportive peer group gatherings, one-on-one connections, and much more. Numerous educational sessions were recorded. If you missed the Conference or would like to revisit sessions, click session titles to link to recordings.

Moderator: Ricky Safer, CEO, PSC Partners

Richard Green, MD, Northwestern University Feinberg School of Medicine

Espen Melum, MD, PhD, Oslo University Hospital

In this session, presenters reviewed the indications for liver transplantation, focusing on the U.S. organ allocation system, the unique opportunity a living donor may provide, and exciting new developments in the field of liver transplantation. Presenters also discuss post-transplantation outcomes and some of the center-specific qualities to consider when choosing care.

Joel Pekow, MD, University of Chicago

Joshua Korzenik, MD, Brigham and Women’s Hospital

This session focused on how IBD may be an important key to understanding PSC. Presenters discussed PSC-IBD research approaches and updates from their ongoing studies.

Johannes Hov, MD, PhD, Oslo University Hospital

This presentation focused on enterohepatic circulation, the gut-liver axis, and the gut microbiota, which form the basis for many hypotheses of PSC etiology. Examples of therapeutic approaches were explored.

Sonya MacParland, PhD, University of Toronto

Mary Pressley Vyas, President, PSC Partners Canada

This session focused on how scientists are exploring the cellular ecosystem of the healthy liver vs. the PSC liver to better understand PSC and potentially identify therapeutic targets for PSC. Presenters discussed the four-year, CZI-funded, patient-partnered collaboration between PSC Partners and a scientific team in Toronto, led by Dr. MacParland. The study is focused on uncovering the cellular drivers of PSC.

Moderator: Joanne Hatchett, RN, MS, FNP-retired, Medical Science Liaison, PSC Partners Seeking a Cure

Matt Frankel, MD, MBA: Chemomab Therapeutics - Chief Medical Officer, Vice President of Drug Development

Shirley Dehn: Escient Pharmaceuticals - Associate Director of Clinical Science

Anthony Loizides, MD: Ipsen Biopharmaceuticals - Medical Director of Clinical Development

Ikenna Okechukwu, MD: Ipsen Biopharmaceuticals - Medical Development Director

Chris Peetz: Mirum Pharmaceuticals, Inc. - President & Chief Executive Officer

Richard Pencek, PhD: Pliant Pharmaceuticals - Senior Director, Clinical Development

These five clinical-trial leaders each presented their company's on-going PSC study.

Moderator: David Goldberg, MD, MSCE, University of Miami School of Medicine

Moderator: Heather Francis, PhD, Indiana University School of Medicine

Moderator: Christopher Bowlus, MD, UC Davis School of Medicine

Questions? Email: grants@pscpartners.org

No matter your background or origin, YOUR specific information is essential in the search for treatments and a cure for PSC. If you are a person with PSC, post-transplant, or a parent/guardian of a pediatric PSC person (17 or under), we hope you will take 30 minutes or less to complete the PSC Partners DEI in PSC survey linked in the button below.

Questions? contactus@PSCPartners.org

ZoomRoom Peer-to-Peer Gatherings

Global PSC Awareness Day is October 29, 2023. It's a day when we spread awareness about our rare disease, and we need your help.

Here are ways you can show your support on October 29th:

Sandi was a fan of musical theater. She often used the messages and songs from her favorite musicals to inspire herself and others. Here, she leans on the musical Annie to provide hope to the PSC community.

"Diagnosis of a rare disease which most people have never heard of is downright terrifying. Many of us feel as kicked about and alone as Little Orphan Annie. We've discovered that we are PSCers in a non-PSC world, and (we) feel it's practically a given that it's going to be a Hard-Knock Life. But, like any good musical, there's a silver lining, (and) The Sun'll Come Out Tomorrow. You can bet your bottom dollar on that, no wishing on a star needed. No matter what life throws at us, and we all know far too well that life can be a big, old bully at times, shining a light on each other and ourselves really does make all the difference."

Who is going to the AASLD Liver Meeting? We are! See you there. Patients and caregivers can attend in person or virtually for just $50. Click HERE for more information. Visit the Patient Advocate, Patient, Caregiver tab.

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